pentobarbital will lower the extent or effect of mavacamten by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
Using barbiturates as sedatives within the postoperative surgical interval and as adjuncts to cancer chemotherapy is very well established
buprenorphine transdermal and pentobarbital equally improve sedation. Stay clear of or Use Alternate Drug. Limit use to clients for whom substitute procedure alternatives are insufficient
Check Closely (one)pentobarbital will lessen the level or effect of benzhydrocodone/acetaminophen by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Caution when discontinuing CYP3A4 inducers which have been coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone may perhaps raise and may end up in possibly fatal respiratory melancholy.
pentobarbital decreases outcomes of hemin by pharmacodynamic antagonism. Use Warning/Monitor. Medicine that improve delta-aminolevulinic acid synthetase may possibly minimize hemin result.
pentobarbital will decrease the level or result of tofacitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Lack of, or lessened response to tofacitinib could arise when coadministered with strong CYP3A4 inducers
Reserve concomitant prescribing of these medication in patients for whom other treatment options are insufficient. Restrict dosages and durations into the minimum amount expected. Watch carefully for indications of respiratory despair and sedation.
Check Closely (1)pentobarbital will lessen the level or outcome of tadalafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will nembutal kaufen lessen the level or influence of armodafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
Therapy should be administered with warning, if at all, to patients who are mentally depressed, have suicidal tendencies, or historical past of drug abuse
pentobarbital will decrease the extent or impact of almotriptan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lessen the level or impact of flurbiprofen by affecting hepatic enzyme CYP2C9/10 metabolism. Insignificant/Significance Unidentified.
pentobarbital will minimize the extent or influence of lumacaftor/ivacaftor by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lower the level or result of glecaprevir/pibrentasvir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.